Using one-molecule optical and AFM imaging and power-spectroscopy methods, we seek to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our investigation interests involve:
You often become involved in discussions about science and religion. You've also penned many books on the topic. Don’t you believe that in some unspecified time in the future We'll know everything and that God’s role is going to be over?
Again in 1991, Sumio Iijima of the NEC Company experienced claimed the synthesis of carbon nanotubes. Band composition calculations prompt that these nanotubes could exhibit metallic band conduction. This may be a big edge about the conducting polymers we experienced explored, which ended up, in truth, disordered semiconductors presenting just variable-array hopping conductivity.
Non-equilibrium folding of specific DNA molecules recaptured approximately one thousand moments within a sound state nanopore
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Microbiology has only existed to get a century, considering that we began to examine micro-organisms additional very seriously. I assumed nanobiology was an correct time period, because all molecular biological relevant interactions take place at the nanoscale: a protein is a couple of nanometres in dimension, DNA is 2 nm thick.’
We use nanofabricated microfluidic buildings to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental position of spatial confinement with the molecular and cellular degree. Our tasks consist of the following:
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in gray, the rim from the pore is highlighted in purple, along with a 3D rendering with the motion with the DNA rod is displayed.
Imagine if, as opposed to using regular best-down silicon electronics, transistors could be designed from the bottom up working with single natural and organic molecules because the switching features? This idea, which turned the basis of currently’s area of molecular electronics, initially emerged inside the nineteen seventies.
It was throughout this period that Dekker performed investigate on magnetic spin units and on sounds in superconductors and semiconductors.
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2001, discovery of single-electron transistors at home temperature based on nanotubes; realization of initial logic circuits with carbon nanotube units; and discovery in the molecular structure of DNA repair enzymes with AFM
Allow’s very first seem back again at the moment whenever you chose to shift your target from superconductivity and nanotubes to biology at the end of the nineties.
The biophysicist from Delft – who has actually been Among the most cited researchers inside the Netherlands For many years – requires his obligation to add on the explanation and popularisation of his work within the border of physics and biology particularly significantly and routinely appears from the media; if not to speak about his work, then about the connection amongst science and his Christian faith.